5-Methyl-4,5,6,7-tetrahydrothiazolo[5,4-c]pyridine-2-carboxylic acid hydrochloride

 Edoxaban intermediate properties Melting point 199.0to203.0 ° C Boiling point 175 ℃ [at101325Pa] Storage conditions Undernertgas (nitroorArgon) at2-8 ° C Solubility AqueousAcid (Slightly), DMSO (Slightly, Heated, Sonicated), Methanol (VerySlig form Solid color PaleBeigotoLightBrown stability Hygrosopic Yidoxaban intermediate use and synthesis method use 5-methyl-4,5,6,7-tetrahydrothiazole [5,4-c] pyridine-2-carboxylic acid hydrochloride as a reagent for the synthesis of N - (2-acylaminobenzyl or 2-acylaminoheterocyclic methyl) thiophene-2 - carboxamide derivatives as antithrombotic agents. It can also be used as a reagent for synthesizing diamine derivatives (FXa inhibitors). 5-methyl-4,5,6,7-tetrahydrothiazolo [5,4-c] pyridin-2-carboxylic acid hydrochloride is the intermediate of Edoxaban (E555520). Usage The intermediate of Yidoxaban can be used as impurity reference substance, and also used for drug declaration and detection.

 Edoxaban intermediate properties Melting point 199.0to203.0 ° C Boiling point 175 ℃ [at101325Pa] Storage conditions Undernertgas (nitroorArgon) at2-8 ° C Solubility AqueousAcid (Slightly), DMSO (Slightly, Heated, Sonicated), Methanol (VerySlig form Solid color PaleBeigotoLightBrown stability Hygrosopic Yidoxaban intermediate use and synthesis method use 5-methyl-4,5,6,7-tetrahydrothiazole [5,4-c] pyridine-2-carboxylic acid hydrochloride as a reagent for the synthesis of N - (2-acylaminobenzyl or 2-acylaminoheterocyclic methyl) thiophene-2 - carboxamide derivatives as antithrombotic agents. It can also be used as a reagent for synthesizing diamine derivatives (FXa inhibitors). 5-methyl-4,5,6,7-tetrahydrothiazolo [5,4-c] pyridin-2-carboxylic acid hydrochloride is the intermediate of Edoxaban (E555520). Usage The intermediate of Yidoxaban can be used as impurity reference substance, and also used for drug declaration and detection.